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Multiple clinically-relevant hormone therapy regimens fail to improve cognitive function in aged ovariectomized rhesus monkeys

Preclinical studies in aged, surgically-menopausal rhesus monkeys have revealed powerful benefits of intermittent estrogen injections on prefrontal cortex-dependent working memory, together with corresponding effects on dendritic spine morphology in the prefrontal cortex. This contrasts with the inc...

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Autors principals: Baxter, Mark G., Roberts, Mary T., Gee, Nancy A., Lasley, Bill L., Morrison, John H., Rapp, Peter R.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622837/
https://ncbi.nlm.nih.gov/pubmed/23369546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2012.12.017
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