Synaptic correlates of memory and menopause in the hippocampal dentate gyrus in rhesus monkeys

Aged rhesus monkeys exhibit deficits in hippocampus-dependent memory, similar to aging humans. Here we explored the basis of cognitive decline by first testing young adult and aged monkeys on a standard recognition memory test (delayed nonmatching-to-sample test; DNMS). Next we quantified synaptic d...

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Main Authors: Hara, Yuko, Park, C. Sehwan, Janssen, William G. M., Roberts, Mary T., Morrison, John H., Rapp, Peter R.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031995/
https://ncbi.nlm.nih.gov/pubmed/21030115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2010.09.014
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