Selective Changes in Thin Spine Density and Morphology in Monkey Prefrontal Cortex Correlate with Aging-Related Cognitive Impairment

Age-associated memory impairment (AAMI) occurs in many mammalian species, including humans. In contrast to Alzheimer's disease (AD), in which circuit disruption occurs through neuron death, AAMI is due to circuit and synapse disruption in the absence of significant neuron loss and thus may be m...

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Detalhes bibliográficos
Main Authors: Dumitriu, Dani, Hao, Jiandong, Hara, Yuko, Kaufmann, Jeffrey, Janssen, William G. M., Lou, Wendy, Rapp, Peter R., Morrison, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892969/
https://ncbi.nlm.nih.gov/pubmed/20519525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6410-09.2010
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