Presynaptic mitochondrial morphology in monkey prefrontal cortex correlates with working memory and is improved with estrogen treatment

Humans and nonhuman primates are vulnerable to age- and menopause-related decline in working memory, a cognitive function reliant on the energy-demanding recurrent excitation of neurons within Brodmann’s Area 46 of the dorsolateral prefrontal cortex (dlPFC). Here, we tested the hypothesis that the n...

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Bibliographische Detailangaben
Hauptverfasser: Hara, Yuko, Yuk, Frank, Puri, Rishi, Janssen, William G. M., Rapp, Peter R., Morrison, John H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2014
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890848/
https://ncbi.nlm.nih.gov/pubmed/24297907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311310110
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