Estrogen Restores Multisynaptic Boutons in the Dorsolateral Prefrontal Cortex while Promoting Working Memory in Aged Rhesus Monkeys

Humans and nonhuman primates are vulnerable to age- and menopause- related decline in working memory, a cognitive function reliant on area 46 of the dorsolateral prefrontal cortex (dlPFC). We showed previously that presynaptic mitochondrial number and morphology in monkey dlPFC neurons correlate wit...

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Vydáno v:J Neurosci
Hlavní autoři: Hara, Yuko, Yuk, Frank, Puri, Rishi, Janssen, William G. M., Rapp, Peter R., Morrison, John H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719022/
https://ncbi.nlm.nih.gov/pubmed/26791219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3480-13.2016
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