Evidence for Reduced Experience-Dependent Dendritic Spine Plasticity in the Aging Prefrontal Cortex

Cognitive functions that require the prefrontal cortex are highly sensitive to aging in humans, nonhuman primates, and rodents, although the neurobiological correlates of this vulnerability remain largely unknown. It has been proposed that dendritic spines represent the primary site of structural pl...

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Main Authors: Bloss, Erik B., Janssen, William G., Ohm, Daniel T., Yuk, Frank J., Wadsworth, Shannon, Saardi, Karl M., McEwen, Bruce S., Morrison, John H.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2011
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398699/
https://ncbi.nlm.nih.gov/pubmed/21613496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0839-11.2011
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