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Development of second generation EP2 antagonists with high selectivity
EP2 receptor has emerged as an important biological target for therapeutic intervention. In particular, it has been shown to exacerbate disease progression of a variety of CNS and peripheral diseases. Deletion of the EP2 receptor in mouse models recapitulates several features of the COX-2 inhibition...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4108197/ https://ncbi.nlm.nih.gov/pubmed/24937185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2014.05.076 |
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