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Discovery and Characterization of Carbamothioylacrylamides As EP2 Selective Antagonists

[Image: see text] Prostanoid receptor EP2 is emerging as a novel target for development of anti-inflammatory drugs for the treatment of chronic neurodegenerative and peripheral diseases; however, the availability of EP2 antagonist probes for exploration of peripheral disease models is very limited....

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Autors principals: Ganesh, Thota, Jiang, Jianxiong, Shashidharamurthy, Rangaiah, Dingledine, Ray
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2013
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731160/
https://ncbi.nlm.nih.gov/pubmed/23914286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400112h
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