A New Positron Emission Tomography (PET) Radioligand for Imaging Sigma-1 Receptors in Living Subjects

Sigma-1 receptor (S1R) radioligands have the potential to detect and monitor various neurological diseases. Herein we report the synthesis, radiofluorination and evaluation of a new S1R ligand 6-(3-fluoropropyl)-3-(2-(azepan-1-yl)ethyl)benzo[d]thiazol-2(3H)-one ([(18)F]FTC-146, [(18)F]13). [(18)F]13...

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Detaylı Bibliyografya
Asıl Yazarlar: James, Michelle L., Shen, Bin, Zavaleta, Cristina L., Nielsen, Carsten H., Mesangeau, Christophe, Vuppala, Pradeep K., Chan, Carmel, Avery, Bonnie A., Fishback, James A., Matsumoto, Rae R., Gambhir, Sanjiv S., McCurdy, Christopher R., Chin, Frederick T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106900/
https://ncbi.nlm.nih.gov/pubmed/22853801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm300371c
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