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Porous silicon oxide-PLGA composite microspheres for sustained ocular delivery of daunorubicin

A water-soluble anthracycline antibiotic drug (daunorubicin, DNR) was loaded into oxidized porous silicon (pSiO(2)) microparticles and then encapsulated with a layer of polymer (poly lactide-co-glycolide, PLGA) to investigate their synergistic effects in control of DNR release. Similarly fabricated...

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Autors principals: Nan, Kaihui, Ma, Feiyan, Hou, Huiyuan, Freeman, William R., Sailor, Michael J., Cheng, Lingyun
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106702/
https://ncbi.nlm.nih.gov/pubmed/24793657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2014.04.024
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