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Controlled Release of Dexamethasone From an Intravitreal Delivery System Using Porous Silicon Dioxide

PURPOSE: The current study aims to evaluate a porous silicon-based drug delivery system meant for sustained delivery of dexamethasone (Dex) to the vitreous and retina. METHODS: Dexamethasone was grafted covalently into the pore walls of fully oxidized porous silicon particles (pSiO(2)-COO-Dex), whic...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Hou, Huiyuan, Wang, Chengyun, Nan, Kaihui, Freeman, William R., Sailor, Michael J., Cheng, Lingyun
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758302/
https://ncbi.nlm.nih.gov/pubmed/26882530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-18559
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