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Ocular silicon distribution and clearance following intravitreal injection of porous silicon microparticles

Porous silicon (pSi) microparticles have been investigated for intravitreal drug delivery and demonstrated good biocompatibility. With the appropriate surface chemistry, pSi can reside in vitreous for months or longer. However, ocular distribution and clearance pathway of its degradation product, si...

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Detalhes bibliográficos
Main Authors: Nieto, Alejandra, Hou, Huiyuan, Sailor, Michael J., Freeman, William R., Cheng, Lingyun
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873878/
https://ncbi.nlm.nih.gov/pubmed/24036388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2013.09.001
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