Tunable sustained intravitreal drug delivery system for daunorubicin using oxidized porous silicon

Daunorubicin (DNR) is an effective inhibitor of an array of proteins involved in neovascularization, including VEGF and PDGF. These growth factors are directly related to retina scar formation in many devastating retinal diseases. Due to the short vitreous half-life and narrow therapeutic window, oc...

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Main Authors: Hou, Huiyuan, Nieto, Alejandra, Ma, Feiyan, Freeman, William R., Sailor, Michael J., Cheng, Lingyun
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951847/
https://ncbi.nlm.nih.gov/pubmed/24424270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2014.01.003
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