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Tunable sustained intravitreal drug delivery system for daunorubicin using oxidized porous silicon

Daunorubicin (DNR) is an effective inhibitor of an array of proteins involved in neovascularization, including VEGF and PDGF. These growth factors are directly related to retina scar formation in many devastating retinal diseases. Due to the short vitreous half-life and narrow therapeutic window, oc...

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Detalhes bibliográficos
Main Authors: Hou, Huiyuan, Nieto, Alejandra, Ma, Feiyan, Freeman, William R., Sailor, Michael J., Cheng, Lingyun
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951847/
https://ncbi.nlm.nih.gov/pubmed/24424270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2014.01.003
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