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Surface Engineering of Porous Silicon Microparticles for Intravitreal Sustained Delivery of Rapamycin

PURPOSE. To understand the relationship between rapamycin loading/release and surface chemistries of porous silicon (pSi) to optimize pSi-based intravitreal delivery system. METHODS. Three types of surface chemical modifications were studied: (1) pSi-COOH, containing 10-carbon aliphatic chains with...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Nieto, Alejandra, Hou, Huiyuan, Moon, Sang Woong, Sailor, Michael J., Freeman, William R., Cheng, Lingyun
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329946/
https://ncbi.nlm.nih.gov/pubmed/25613937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-15997
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