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The RNA binding domain of Pumilio antagonizes poly-adenosine binding protein and accelerates deadenylation

PUF proteins are potent repressors that serve important roles in stem cell maintenance, neurological processes, and embryonic development. These functions are driven by PUF protein recognition of specific binding sites within the 3′ untranslated regions of target mRNAs. In this study, we investigate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Weidmann, Chase A., Raynard, Nathan A., Blewett, Nathan H., Van Etten, Jamie, Goldstrohm, Aaron C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105754/
https://ncbi.nlm.nih.gov/pubmed/24942623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.046029.114
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