Drosophila Nanos acts as a molecular clamp that modulates the RNA-binding and repression activities of Pumilio

Collaboration among the multitude of RNA-binding proteins (RBPs) is ubiquitous, yet our understanding of these key regulatory complexes has been limited to single RBPs. We investigated combinatorial translational regulation by Drosophila Pumilio (Pum) and Nanos (Nos), which control development, fert...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Weidmann, Chase A, Qiu, Chen, Arvola, René M, Lou, Tzu-Fang, Killingsworth, Jordan, Campbell, Zachary T, Tanaka Hall, Traci M, Goldstrohm, Aaron C
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Biophysics and Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995099/
https://ncbi.nlm.nih.gov/pubmed/27482653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.17096
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