Drosophila Nanos acts as a molecular clamp that modulates the RNA-binding and repression activities of Pumilio

Collaboration among the multitude of RNA-binding proteins (RBPs) is ubiquitous, yet our understanding of these key regulatory complexes has been limited to single RBPs. We investigated combinatorial translational regulation by Drosophila Pumilio (Pum) and Nanos (Nos), which control development, fert...

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Bibliographic Details
Published in:eLife
Main Authors: Weidmann, Chase A, Qiu, Chen, Arvola, René M, Lou, Tzu-Fang, Killingsworth, Jordan, Campbell, Zachary T, Tanaka Hall, Traci M, Goldstrohm, Aaron C
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2016
Subjects:
Biophysics and Structural Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995099/
https://ncbi.nlm.nih.gov/pubmed/27482653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.17096
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