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Human Pumilio Proteins Recruit Multiple Deadenylases to Efficiently Repress Messenger RNAs

PUF proteins are a conserved family of eukaryotic RNA-binding proteins that regulate specific mRNAs: they control many processes including stem cell proliferation, fertility, and memory formation. PUFs repress protein expression from their target mRNAs but the mechanism by which they do so remains u...

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Bibliographic Details
Main Authors: Van Etten, Jamie, Schagat, Trista L., Hrit, Joel, Weidmann, Chase A., Brumbaugh, Justin, Coon, Joshua J., Goldstrohm, Aaron C.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476303/
https://ncbi.nlm.nih.gov/pubmed/22955276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.373522
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