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The RNA binding domain of Pumilio antagonizes poly-adenosine binding protein and accelerates deadenylation

PUF proteins are potent repressors that serve important roles in stem cell maintenance, neurological processes, and embryonic development. These functions are driven by PUF protein recognition of specific binding sites within the 3′ untranslated regions of target mRNAs. In this study, we investigate...

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Detalhes bibliográficos
Main Authors: Weidmann, Chase A., Raynard, Nathan A., Blewett, Nathan H., Van Etten, Jamie, Goldstrohm, Aaron C.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105754/
https://ncbi.nlm.nih.gov/pubmed/24942623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.046029.114
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