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The RNA binding domain of Pumilio antagonizes poly-adenosine binding protein and accelerates deadenylation

PUF proteins are potent repressors that serve important roles in stem cell maintenance, neurological processes, and embryonic development. These functions are driven by PUF protein recognition of specific binding sites within the 3′ untranslated regions of target mRNAs. In this study, we investigate...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Weidmann, Chase A., Raynard, Nathan A., Blewett, Nathan H., Van Etten, Jamie, Goldstrohm, Aaron C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105754/
https://ncbi.nlm.nih.gov/pubmed/24942623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.046029.114
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