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Deafness induced by Connexin26 (GJB2) deficiency is not determined by endocochlear potential (EP) reduction but is associated with cochlear developmental disorders

Connexin 26 (Cx26, GJB2) mutations are the major cause of hereditary deafness and are responsible for >50% of nonsyndromic hearing loss. Mouse models show that Cx26 deficiency can cause congenital deafness with cochlear developmental disorders, hair cell degeneration, and the reduction of endococ...

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Hlavní autoři: Chen, Jin, Chen, Jing, Zhu, Yan, Liang, Chun, Zhao, Hong-Bo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105360/
https://ncbi.nlm.nih.gov/pubmed/24732355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.04.016
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