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Connexin26 (GJB2) deficiency reduces active cochlear amplification leading to late-onset hearing loss

Connexin26 (Cx26, GJB2) mutations account for >50% of nonsyndromic hearing loss. The deafness is not always congenital. A large group of these patients (~30%) demonstrate a late-onset hearing loss, starting in childhood. They have normal hearing early in life and are therefore good candidates for...

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Dettagli Bibliografici
Pubblicato in:Neuroscience
Autori principali: Zhu, Yan, Chen, Jin, Liang, Chun, Zong, Liang, Chen, Jing, Jones, Raleigh O., Zhao, Hong-Bo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268423/
https://ncbi.nlm.nih.gov/pubmed/25451287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2014.10.061
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