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Cell degeneration is not a primary causer for Connexin26 (GJB2) deficiency associated hearing loss
Connexin 26 (Cx26, GJB2) mutations can induce congenital deafness and are responsible for ~50 % of nonsyndromic hearing loss in children. Mouse models show that Cx26 deficiency induces cochlear development disorder, hair cell loss, and spiral ganglion (SG) neuron degeneration. Hair cell loss and cel...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3467974/ https://ncbi.nlm.nih.gov/pubmed/22975134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2012.08.085 |
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