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Cell degeneration is not a primary causer for Connexin26 (GJB2) deficiency associated hearing loss

Connexin 26 (Cx26, GJB2) mutations can induce congenital deafness and are responsible for ~50 % of nonsyndromic hearing loss in children. Mouse models show that Cx26 deficiency induces cochlear development disorder, hair cell loss, and spiral ganglion (SG) neuron degeneration. Hair cell loss and cel...

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Detalhes bibliográficos
Main Authors: Liang, Chun, Zhu, Yan, Zong, Liang, Lu, Guang-Jin, Zhao, Hong-Bo
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467974/
https://ncbi.nlm.nih.gov/pubmed/22975134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2012.08.085
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