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Cell degeneration is not a primary causer for Connexin26 (GJB2) deficiency associated hearing loss

Connexin 26 (Cx26, GJB2) mutations can induce congenital deafness and are responsible for ~50 % of nonsyndromic hearing loss in children. Mouse models show that Cx26 deficiency induces cochlear development disorder, hair cell loss, and spiral ganglion (SG) neuron degeneration. Hair cell loss and cel...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liang, Chun, Zhu, Yan, Zong, Liang, Lu, Guang-Jin, Zhao, Hong-Bo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467974/
https://ncbi.nlm.nih.gov/pubmed/22975134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2012.08.085
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