Progranulin protein levels are differently regulated in plasma and CSF

OBJECTIVE: We aimed to investigate the relationship between plasma and CSF progranulin (PGRN) levels. METHODS: Plasma and CSF PGRN were measured in a cohort of 345 subjects from the Mayo Clinic Study of Aging by ELISA. Single nucleotide polymorphism genotyping was performed using TaqMan assays. Asso...

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Bibliografiset tiedot
Päätekijät: Nicholson, Alexandra M., Finch, NiCole A., Thomas, Colleen S., Wojtas, Aleksandra, Rutherford, Nicola J., Mielke, Michelle M., Roberts, Rosebud O., Boeve, Bradley F., Knopman, David S., Petersen, Ronald C., Rademakers, Rosa
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Lippincott Williams & Wilkins 2014
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105255/
https://ncbi.nlm.nih.gov/pubmed/24771538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000000445
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