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Progranulin protein levels are differently regulated in plasma and CSF

OBJECTIVE: We aimed to investigate the relationship between plasma and CSF progranulin (PGRN) levels. METHODS: Plasma and CSF PGRN were measured in a cohort of 345 subjects from the Mayo Clinic Study of Aging by ELISA. Single nucleotide polymorphism genotyping was performed using TaqMan assays. Asso...

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Main Authors: Nicholson, Alexandra M., Finch, NiCole A., Thomas, Colleen S., Wojtas, Aleksandra, Rutherford, Nicola J., Mielke, Michelle M., Roberts, Rosebud O., Boeve, Bradley F., Knopman, David S., Petersen, Ronald C., Rademakers, Rosa
Formato: Artigo
Idioma:Inglês
Publicado: Lippincott Williams & Wilkins 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105255/
https://ncbi.nlm.nih.gov/pubmed/24771538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000000445
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