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HUMAN GENETICS AS A TOOL TO IDENTIFY PROGRANULIN REGULATORS

Frontotemporal lobar degeneration (FTLD) is a common neurodegenerative disorder that predominantly affects individuals under the age of 65. It is known that the most common pathological subtype is FTLD with TAR DNA-binding protein 43 inclusions (FTLD-TDP). FTLD has a strong genetic component with ab...

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Bibliographic Details
Main Authors: Nicholson, Alexandra M., Finch, NiCole A., Rademakers, Rosa
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310391/
https://ncbi.nlm.nih.gov/pubmed/21626010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-011-9554-y
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