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Methods for integration site distribution analyses in animal cell genomes

The question of where retroviral DNA becomes integrated in chromosomes is important for understanding (i) the mechanisms of viral growth, (ii) devising new anti-retroviral therapy, (iii) understanding how genomes evolve, and (iv) developing safer methods for gene therapy. With the completion of geno...

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Autores principales: Ciuffi, Angela, Ronen, Keshet, Brady, Troy, Malani, Nirav, Wang, Gary, Berry, Charles C., Bushman, Frederic D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104535/
https://ncbi.nlm.nih.gov/pubmed/19038346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2008.10.028
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