Integration target site selection by a resurrected human endogenous retrovirus

At least 8% of the human genome was formed by integration of retroviral DNA sequences. Here we analyze the forces directing the accumulation of human endogenous retroviruses (HERVs) by comparing de novo HERV integration targeting with the distribution of fixed HERV elements in the human genome. All...

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Bibliographic Details
Main Authors: Brady, Troy, Lee, Young Nam, Ronen, Keshet, Malani, Nirav, Berry, Charles C., Bieniasz, Paul D., Bushman, Frederic D.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2009
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658518/
https://ncbi.nlm.nih.gov/pubmed/19270161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1762309
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