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Methods for integration site distribution analyses in animal cell genomes

The question of where retroviral DNA becomes integrated in chromosomes is important for understanding (i) the mechanisms of viral growth, (ii) devising new anti-retroviral therapy, (iii) understanding how genomes evolve, and (iv) developing safer methods for gene therapy. With the completion of geno...

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Hlavní autoři: Ciuffi, Angela, Ronen, Keshet, Brady, Troy, Malani, Nirav, Wang, Gary, Berry, Charles C., Bushman, Frederic D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104535/
https://ncbi.nlm.nih.gov/pubmed/19038346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2008.10.028
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