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Comparing DNA integration site clusters with scan statistics

Motivation: Gene therapy with retroviral vectors can induce adverse effects when those vectors integrate in sensitive genomic regions. Retroviral vectors are preferred that target sensitive regions less frequently, motivating the search for localized clusters of integration sites and comparison of t...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Berry, Charles C., Ocwieja, Karen E., Malani, Nirav, Bushman, Frederic D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029028/
https://ncbi.nlm.nih.gov/pubmed/24489369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu035
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