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Comparing DNA integration site clusters with scan statistics

Motivation: Gene therapy with retroviral vectors can induce adverse effects when those vectors integrate in sensitive genomic regions. Retroviral vectors are preferred that target sensitive regions less frequently, motivating the search for localized clusters of integration sites and comparison of t...

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Detalhes bibliográficos
Main Authors: Berry, Charles C., Ocwieja, Karen E., Malani, Nirav, Bushman, Frederic D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029028/
https://ncbi.nlm.nih.gov/pubmed/24489369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu035
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