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Transgenic overexpression of the presynaptic choline transporter elevates acetylcholine levels and augments motor endurance
The hemicholinium-3 (HC-3) sensitive, high-affinity choline transporter (CHT) sustains cholinergic signaling via the presynaptic uptake of choline derived from dietary sources or from acetylcholinesterase (AChE)-mediated hydrolysis of acetylcholine (ACh). Loss of cholinergic signaling capacity is as...
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| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4104494/ https://ncbi.nlm.nih.gov/pubmed/24274995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2013.11.008 |
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