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Development of inhibitors of heterotrimeric Gα(i) subunits
Heterotrimeric G-proteins are the immediate downstream effectors of G-protein coupled receptors (GPCRs). Endogenous protein guanine nucleotide dissociation inhibitors (GDIs) like AGS3/4 and RGS12/14 function through GPR/Goloco GDI domains. Extensive characterization of GPR domain peptides indicate t...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4103618/ https://ncbi.nlm.nih.gov/pubmed/24818958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.04.035 |
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