Two waves of de novo methylation during mouse germ cell development

During development, mammalian germ cells reprogram their epigenomes via a genome-wide erasure and de novo rewriting of DNA methylation marks. We know little of how methylation patterns are specifically determined. The piRNA pathway is thought to target the bulk of retrotransposon methylation. Here w...

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Bibliografische gegevens
Hoofdauteurs: Molaro, Antoine, Falciatori, Ilaria, Hodges, Emily, Aravin, Alexei A., Marran, Krista, Rafii, Shahin, McCombie, W. Richard, Smith, Andrew D., Hannon, Gregory J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2014
Onderwerpen:
Research Communication
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102761/
https://ncbi.nlm.nih.gov/pubmed/25030694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.244350.114
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