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Sperm methylation profiles reveal features of epigenetic inheritance and evolution in primates
During germ cell and preimplantation development, mammalian cells undergo nearly complete reprogramming of DNA methylation patterns. We profiled the methylomes of human and chimp sperm as a basis for comparison to methylation patterns of ES cells. While the majority of promoters escape methylation i...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3205962/ https://ncbi.nlm.nih.gov/pubmed/21925323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.08.016 |
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