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Genomic landscape of human allele-specific DNA methylation

DNA methylation mediates imprinted gene expression by passing an epigenomic state across generations and differentially marking specific regulatory regions on maternal and paternal alleles. Imprinting has been tied to the evolution of the placenta in mammals and defects of imprinting have been assoc...

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Autores principales: Fang, Fang, Hodges, Emily, Molaro, Antoine, Dean, Matthew, Hannon, Gregory J., Smith, Andrew D.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358917/
https://ncbi.nlm.nih.gov/pubmed/22523239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201310109
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