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Sperm methylation profiles reveal features of epigenetic inheritance and evolution in primates
During germ cell and preimplantation development, mammalian cells undergo nearly complete reprogramming of DNA methylation patterns. We profiled the methylomes of human and chimp sperm as a basis for comparison to methylation patterns of ES cells. While the majority of promoters escape methylation i...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3205962/ https://ncbi.nlm.nih.gov/pubmed/21925323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.08.016 |
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