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Small RNA guides for de novo DNA methylation in mammalian germ cells

Germline genomic methylation is essential for gamete identity and integrity in mammals. The study by Kuramochi-Miyagawa and colleagues (908–917) in the previous issue of Genes & Development links the process of DNA methylation-dependent repression of retrotranspons with the presence of piwi-inte...

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Detalhes bibliográficos
Main Authors: Aravin, Alexei A., Bourc’his, Déborah
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732394/
https://ncbi.nlm.nih.gov/pubmed/18413711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1669408
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