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Dynamic Evolution of De Novo DNA Methyltransferases in Rodent and Primate Genomes

Transcriptional silencing of retrotransposons via DNA methylation is paramount for mammalian fertility and reproductive fitness. During germ cell development, most mammalian species utilize the de novo DNA methyltransferases DNMT3A and DNMT3B to establish DNA methylation patterns. However, many rode...

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Foilsithe in:Mol Biol Evol
Main Authors: Molaro, Antoine, Malik, Harmit S, Bourc’his, Deborah
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306680/
https://ncbi.nlm.nih.gov/pubmed/32077945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msaa044
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