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Modeling the specificity of protein-DNA interactions

The specificity of protein-DNA interactions is most commonly modeled using position weight matrices (PWMs). First introduced in 1982, they have been adapted to many new types of data and many different approaches have been developed to determine the parameters of the PWM. New high-throughput technol...

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Hlavní autor: Stormo, Gary D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101922/
https://ncbi.nlm.nih.gov/pubmed/25045190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40484-013-0012-4
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