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Modeling the specificity of protein-DNA interactions

The specificity of protein-DNA interactions is most commonly modeled using position weight matrices (PWMs). First introduced in 1982, they have been adapted to many new types of data and many different approaches have been developed to determine the parameters of the PWM. New high-throughput technol...

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Détails bibliographiques
Auteur principal: Stormo, Gary D.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101922/
https://ncbi.nlm.nih.gov/pubmed/25045190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40484-013-0012-4
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