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Modeling tandem AAG8-MEK inhibition in melanoma cells

Drug resistance presents a challenge to the treatment of cancer patients, especially for melanomas, most of which are caused by the hyperactivation of MAPK signaling pathway. Innate or acquired drug-resistant relapse calls for the investigation of the resistant mechanisms and new anti-cancer drugs t...

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Autors principals: Sun, Bing, Kawahara, Masahiro, Nagamune, Teruyuki
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101763/
https://ncbi.nlm.nih.gov/pubmed/24634165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.233
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