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Construction of antibody/insulin receptor chimera for growth induction of mammalian cells

The insulin receptor (IR) is expressed ubiquitously in various tissues, where insulin exerts various biological effects on the target cells, such as cellular metabolic changes, cell proliferation and differentiation. Therefore, mimicry of insulin signaling would be a promising strategy to realize ar...

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Detalhes bibliográficos
Main Authors: Nakabayashi, Hideto, Kawahara, Masahiro, Tanaka, Kento, Nagamune, Teruyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853637/
https://ncbi.nlm.nih.gov/pubmed/23615961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-013-9571-5
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