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Construction of antibody/insulin receptor chimera for growth induction of mammalian cells
The insulin receptor (IR) is expressed ubiquitously in various tissues, where insulin exerts various biological effects on the target cells, such as cellular metabolic changes, cell proliferation and differentiation. Therefore, mimicry of insulin signaling would be a promising strategy to realize ar...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer Netherlands
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3853637/ https://ncbi.nlm.nih.gov/pubmed/23615961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-013-9571-5 |
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