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Construction of antibody/insulin receptor chimera for growth induction of mammalian cells

The insulin receptor (IR) is expressed ubiquitously in various tissues, where insulin exerts various biological effects on the target cells, such as cellular metabolic changes, cell proliferation and differentiation. Therefore, mimicry of insulin signaling would be a promising strategy to realize ar...

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Sonraí Bibleagrafaíochta
Main Authors: Nakabayashi, Hideto, Kawahara, Masahiro, Tanaka, Kento, Nagamune, Teruyuki
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer Netherlands 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853637/
https://ncbi.nlm.nih.gov/pubmed/23615961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-013-9571-5
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