In Barrett's esophagus patients and Barrett's cell lines, ursodeoxycholic acid increases antioxidant expression and prevents DNA damage by bile acids

Hydrophobic bile acids like deoxycholic acid (DCA), which cause oxidative DNA damage and activate NF-κB in Barrett's metaplasia, might contribute to carcinogenesis in Barrett's esophagus. We have explored mechanisms whereby ursodeoxycholic acid (UDCA, a hydrophilic bile acid) protects agai...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Peng, Sui, Huo, Xiaofang, Rezaei, Davood, Zhang, Qiuyang, Zhang, Xi, Yu, Chunhua, Asanuma, Kiyotaka, Cheng, Edaire, Pham, Thai H., Wang, David H., Chen, Minhu, Souza, Rhonda F., Spechler, Stuart Jon
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2014
Matèries:
Call for Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101678/
https://ncbi.nlm.nih.gov/pubmed/24852569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00085.2014
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars