In Barrett's esophagus patients and Barrett's cell lines, ursodeoxycholic acid increases antioxidant expression and prevents DNA damage by bile acids

Hydrophobic bile acids like deoxycholic acid (DCA), which cause oxidative DNA damage and activate NF-κB in Barrett's metaplasia, might contribute to carcinogenesis in Barrett's esophagus. We have explored mechanisms whereby ursodeoxycholic acid (UDCA, a hydrophilic bile acid) protects agai...

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Xehetasun bibliografikoak
Egile Nagusiak: Peng, Sui, Huo, Xiaofang, Rezaei, Davood, Zhang, Qiuyang, Zhang, Xi, Yu, Chunhua, Asanuma, Kiyotaka, Cheng, Edaire, Pham, Thai H., Wang, David H., Chen, Minhu, Souza, Rhonda F., Spechler, Stuart Jon
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2014
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Call for Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101678/
https://ncbi.nlm.nih.gov/pubmed/24852569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00085.2014
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