Deoxycholic acid causes DNA damage while inducing apoptotic resistance through NF-κB activation in benign Barrett's epithelial cells

Gastroesophageal reflux is associated with adenocarcinoma in Barrett's esophagus, but the incidence of this tumor is rising, despite widespread use of acid-suppressing medications. This suggests that refluxed material other than acid might contribute to carcinogenesis. We looked for potentially...

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Detalhes bibliográficos
Main Authors: Huo, Xiaofang, Juergens, Stefanie, Zhang, Xi, Rezaei, Davood, Yu, Chunhua, Strauch, Eric D., Wang, Jian-Ying, Cheng, Edaire, Meyer, Frank, Wang, David H., Zhang, Qiuyang, Spechler, Stuart J., Souza, Rhonda F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154602/
https://ncbi.nlm.nih.gov/pubmed/21636532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00092.2011
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