Targeting the intrinsic inflammatory pathway: honokiol exerts proapoptotic effects through STAT3 inhibition in transformed Barrett's cells

One way to link chronic inflammation with cancer is through the intrinsic inflammatory pathway, in which genetic alterations that induce malignant transformation also produce a cancer-promoting, inflammatory microenvironment. Signal transducer and activator of transcription 3 (STAT3) contributes to...

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Hlavní autoři: Yu, Chunhua, Zhang, Qiuyang, Zhang, Hui Ying, Zhang, Xi, Huo, Xiaofang, Cheng, Edaire, Wang, David H., Arbiser, Jack L., Spechler, Stuart Jon, Souza, Rhonda F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2012
Témata:
Mucosal Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468554/
https://ncbi.nlm.nih.gov/pubmed/22744336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00033.2012
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