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Rag GTPases are cardioprotective by regulating lysosomal function
The Rag family proteins are Ras-like small GTPases that play a critical role in amino acid-stimulated mTORC1 activation by recruiting mTORC1 to lysosome. Despite progress in the mechanistic understanding of Rag GTPases in mTORC1 activation, little is known about the physiological function of Rag GTP...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4100214/ https://ncbi.nlm.nih.gov/pubmed/24980141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5241 |
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