Late-life rapamycin treatment reverses age-related heart dysfunction

Rapamycin has been shown to extend lifespan in numerous model organisms including mice, with the most dramatic longevity effects reported in females. However, little is known about the functional ramifications of this longevity-enhancing paradigm in mammalian tissues. We treated 24-month-old female...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Flynn, James M., O’Leary, Monique N., Zambataro, Christopher A., Academia, Emmeline C., Presley, Michael P., Garrett, Brittany J., Zykovich, Artem, Mooney, Sean D., Strong, Randy, Rosen, Clifford J., Kapahi, Pankaj, Nelson, Michael D., Kennedy, Brian K., Melov, Simon
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098908/
https://ncbi.nlm.nih.gov/pubmed/23734717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12109
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg