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Hypoxic pulmonary blood flow redistribution and arterial oxygenation in endotoxin-challenged NOS2-deficient mice

Sepsis and endotoxemia impair hypoxic pulmonary vasoconstriction (HPV), thereby reducing arterial oxygenation and enhancing hypoxemia. Endotoxin induces nitric oxide (NO) production by NO synthase 2 (NOS2). To assess the role of NO and NOS2 in the impairment of HPV during endotoxemia, we measured in...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Ullrich, Roman, Bloch, Kenneth D., Ichinose, Fumito, Steudel, Wolfgang, Zapol, Warren M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 1999
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC409836/
https://ncbi.nlm.nih.gov/pubmed/10562304
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