5-Lipoxygenase Deficiency Prevents Respiratory Failure during Ventilator-induced Lung Injury

Rationale: Mechanical ventilation with high VT (HVT) progressively leads to lung injury and decreased efficiency of gas exchange. Hypoxic pulmonary vasoconstriction (HPV) directs blood flow to well-ventilated lung regions, preserving systemic oxygenation during pulmonary injury. Recent experimental...

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Main Authors: Caironi, Pietro, Ichinose, Fumito, Liu, Rong, Jones, Rosemary C., Bloch, Kenneth D., Zapol, Warren M.
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2005
Assuntos:
C. Critical Care
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718472/
https://ncbi.nlm.nih.gov/pubmed/15894604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200501-034OC
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